Brain Mechanisms Contributing to Sympathetic Hyperactivity and Heart Failure

• Published in: Circulation research Vol. 101; no. 3; pp. 221 - 223
• Main Author: Leenen, Frans H.H
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD American Heart Association, Inc 03-08-2007; Lippincott
• Subjects: Angiotensinogen - antagonists & inhibitors; Angiotensinogen - genetics; Animals; Animals, Genetically Modified; Biological and medical sciences; Cardiology. Vascular system; Fundamental and applied biological sciences. Psychology; Gene Transfer Techniques; Heart; Heart Failure - etiology; Heart Failure - physiopathology; Heart failure, cardiogenic pulmonary edema, cardiac enlargement; Infusions, Parenteral; Interleukin-10 - genetics; Interleukin-10 - physiology; Medical sciences; Models, Cardiovascular; Models, Neurological; Myocardial Infarction - complications; Norepinephrine - blood; Paraventricular Hypothalamic Nucleus - metabolism; Paraventricular Hypothalamic Nucleus - physiopathology; Rats; Rats, Sprague-Dawley; RNA, Antisense - genetics; RNA, Antisense - pharmacology; RNA, Messenger - antagonists & inhibitors; Spironolactone - administration & dosage; Spironolactone - pharmacology; Supraoptic Nucleus - physiopathology; Sympathetic Nervous System - physiopathology; Ventricular Remodeling; Vertebrates: cardiovascular system; Mineralocorticoid; Hyperactivity; Peptide hormone; Central nervous system; Cardiovascular disease; Hypothalamus; Aldosterone; Encephalon; Octapeptide; Autonomic nervous system; Heart disease; cardiac function; Angiotensin II; Heart failure; proinflammatory cytokines; Steroid hormone; Cytokine; sympathetic activity; Inflammation; Sympathetic nervous system; Renin angiotensin system; Vertebrata; Mammalia; Adrenal hormone; Circulatory system
• ISSN: 0009-7330; 1524-4571
• DOI: 10.1161/CIRCRESAHA.107.158261