Current concepts on burn wound conversion—A review of recent advances in understanding the secondary progressions of burns

Highlights • We review recent progress in the pathophysiology of burn wound conversion. • Halting burn progression will impact on the scar outcome and healing trajectory. • Ischemia, inflammation, oxygen radicals are well accepted – autophagy is a new concept.

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Bibliographic Details
Published in:	Burns Vol. 42; no. 5; pp. 1025 - 1035
Main Authors:	Salibian, Ara A, Rosario, Angelica Tan Del, Severo, Lucio De Almeida Moura, Nguyen, Long, Banyard, Derek A, Toranto, Jason D, Evans, Gregory R.D, Widgerow, Alan D
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01-08-2016
Subjects:	Autophagy Autophagy - physiology Burn wound conversion Burns - complications Burns - pathology Burns - physiopathology Cicatrix Critical Care Disease Progression Humans Inflammation - physiopathology Ischemia - physiopathology Reactive Oxygen Species - metabolism Secondary burn progression Wound Healing - physiology Burn wound conversion Autophagy Secondary burn progression
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Description
Summary:	Highlights • We review recent progress in the pathophysiology of burn wound conversion. • Halting burn progression will impact on the scar outcome and healing trajectory. • Ischemia, inflammation, oxygen radicals are well accepted – autophagy is a new concept.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 Senior authors
ISSN:	0305-4179 1879-1409
DOI:	10.1016/j.burns.2015.11.007