An Additional Motor-Related Field in the Lateral Frontal Cortex of Squirrel Monkeys

• Published in: Cerebral cortex (New York, N.Y. 1991) Vol. 18; no. 12; pp. 2719 - 2728
• Main Authors: Dancause, Numa, Duric, Vanja, Barbay, Scott, Frost, Shawn B., Stylianou, Antonis, Nudo, Randolph J.
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01-12-2008; Oxford Publishing Limited (England)
• Subjects: Animals; Arm - innervation; Arm - physiology; Brain Mapping; Electric Stimulation; Electromyography; Evoked Potentials - physiology; frontal lateral cortex; Frontal Lobe - anatomy & histology; Frontal Lobe - physiology; frontal rostral area; intracortical microstimulation; Male; Microelectrodes; Motor Activity - physiology; motor control; neuroanatomy; Reaction Time; Saimiri; Saimiri - anatomy & histology; Spinal Cord - anatomy & histology; ventral premotor cortex; frontal rostral area; intracortical microstimulation, motor control; neuroanatomy; ventral premotor cortex; frontal lateral cortex
• ISSN: 1047-3211; 1460-2199
• DOI: 10.1093/cercor/bhn050

Our earlier efforts to document the cortical connections of the ventral premotor cortex (PMv) revealed dense connections with a field rostral and lateral to PMv, an area we called the frontal rostral field (FR). Here, we present data collected in FR using electrophysiological and anatomical methods. Results show that FR contains an isolated motor representation of the forelimb that can be differentiated from PMv based on current thresholds and latencies to evoke electromyographic activity using intracortical microstimulation techniques. In addition, FR has a different pattern of cortical connections compared with PMv. Together, these data support that FR is an additional, previously undescribed motor-related area in squirrel monkeys.