Attainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in Sri Lanka

• Published in: Diabetes, metabolic syndrome and obesity Vol. 11; pp. 409 - 415
• Main Authors: Weerarathna, Thilak Priyantha, Herath, Herath Mudiyanselage Meththananda, Liyanage, Gayani, Weerarathna, Miyuru Kavinda, Senadheera, Vidarsha
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 01-01-2018; Taylor & Francis Ltd; Dove Medical Press
• Subjects: Blood glucose; Blood lipids; Cardiac patients; Cardiovascular disease; Cardiovascular diseases; Cardiovascular risk factors; Care and treatment; Cholesterol; Complications and side effects; Diabetes; Diabetes mellitus; Diabetes therapy; Glucose; Glycosylated hemoglobin; Health aspects; Health risk assessment; Health screening; Hemoglobins; Lipids; Low density lipoproteins; Medical research; Mortality; Original Research; Prevention; Regression analysis; Risk factors; Sri Lanka; therapeutic targets; Type 2 diabetes; Sri Lanka; United States > US; type 2 diabetes mellitus; therapeutic targets; Sri Lanka; suboptimal control
• ISSN: 1178-7007; 1178-7007
• DOI: 10.2147/DMSO.S172485

Implementation of effective measures to control rising burden of cardiovascular diseases among patients with type 2 diabetes mellitus (T2DM) requires information on the adequacy of control and identification of specific groups with suboptimal control of blood glucose, lipids and blood pressure.
A cross-sectional study of patients with T2DM referred from primary care to a diabetes center was carried out to estimate the proportion of patients achieving the recommended therapeutic targets of four major modifiable cardiovascular risk factors: glycosylated hemoglobin (HbA1c <7%), low-density lipoprotein cholesterol <100 mg/dL, systolic blood pressure (SBP) <130 mmHg and diastolic blood pressure (DBP) <80 mmHg and their associations with age, gender, duration of diabetes and body mass index were studied.
Mean (SD) age and the duration of the sample of 2422 (65% males) were 52 (11) and 9 (3), respectively. Percentages with optimal HbA1c, low-density lipoprotein cholesterol, SBP and DBP were 25.2%, 24.3%, 32% and 56.7%, respectively. Only 2% had achieved optimal control of all four risk factors. Significantly higher percentages of males were having optimal HbA1C, SBP and DBP, and regression analysis revealed that male gender was significantly associated with optimal control of SBP.
Control of cardiovascular risk diseases factors among patients with T2DM managed in the primary care settings needs further improvements in target achievement in all four modifiable risk factors.