Site-Directed Delivery of VEGF-Targeted Liposomes into Intracranial C6 Glioma

The efficiency of conventional chemotherapy for aggressive tumors in the CNS remains low and new strategies for the targeted delivery of anti-tumor substances are now actively developed. Pegylated liposomes covalently conjugated with monoclonal antibodies to VEGF synthesized by us are nanoparticle c...

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Bibliographic Details
Published in:	Bulletin of experimental biology and medicine Vol. 158; no. 3; pp. 371 - 376
Main Authors:	Shein, S. A., Nukolova, N. V., Korchagina, A. A., Abakumova, T. O., Kiuznetsov, I. I., Abakumov, M. A., Baklaushev, V. P., Gurina, O. I., Chekhonin, V. P.
Format:	Journal Article
Language:	English
Published:	Boston Springer US 01-01-2015 Springer Springer Nature B.V
Subjects:	Animals Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - therapeutic use Biomedical and Life Sciences Biomedicine Brain Neoplasms - drug therapy Cancer Cell Biology Cell Line, Tumor Chemotherapy Female Glioma - drug therapy Gliomas Internal Medicine Laboratory Medicine Liposomes - administration & dosage Liposomes - chemistry Monoclonal antibodies Pathology Proteins Rats Rats, Wistar Vascular endothelial growth factor Vascular Endothelial Growth Factor A - antagonists & inhibitors Vascular Endothelial Growth Factor A - immunology vascular endothelial growth factor (VEGF) brain tumors liposomes target delivery monoclonal antibodies
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