Primary mucinous eccrine adenocarcinoma: A rare skin adnexal tumor at an unusual site

• Published in: Journal of cytology Vol. 36; no. 1; pp. 71 - 72
• Main Authors: Goyal, Rachna, Tanveer, Nadeem, Singh, Usha
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01-01-2019; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Abdomen; Adenocarcinoma; CAT scans; Cellular biology; Colon; Cytology; Diagnosis; Differential diagnosis; Images in Cytopathology; Immunohistochemistry; Metastases; Metastasis; Mucin; Patients; Radiology; Skin; Tumor cells; Tumors
• ISSN: 0970-9371; 0974-5165
• DOI: 10.4103/JOC.JOC_28_18

The extracellular mucin was periodic acid Schiff (PAS) and Alcian blue positive [Figure 2]a and [Figure 2]b. On immunohistochemistry, the tumor cells were positive for CK 7 and negative for CK 20 which supported the eccrine origin of the tumor [Figure 2]c and [Figure 2]d. The final histopathological diagnosis of primary eccrine mucinous adenocarcinoma was given. Metastatic tumors from breast and colon most closely mimic primary eccrine mucinous carcinoma of the skin. [...]primary mucinous eccrine carcinoma of the skin should be considered in the differential diagnosis of mucinous carcinoma on aspiration cytology of subcutaneous masses even at rare sites such as periumbilical region.