Immunohistochemical Localization of SERCA2 in the Ameloblasts of Rat Incisors

Sarcoplasmic or endoplasmic reticulum Ca2+ ATPase (SERCA2) was localized in the ameloblasts of rat incisors by immunohistochemistry. Secretion ameloblasts and maturation ameloblasts, including both ruffle-ended and smooth-ended cells, were labeled with anti-SERCA2 antibodies, with maturation amelobl...

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Bibliographic Details
Published in:	ACTA HISTOCHEMICA ET CYTOCHEMICA Vol. 36; no. 4; pp. 331 - 334
Main Author:	Nishikawa, Sumio
Format:	Journal Article
Language:	English
Published:	Sendai JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 01-01-2003 Japan Science and Technology Agency
Subjects:	ameloblasts immunofluorescence microscopy rat incisor SERCA2
Online Access:	Get full text
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Summary:	Sarcoplasmic or endoplasmic reticulum Ca2+ ATPase (SERCA2) was localized in the ameloblasts of rat incisors by immunohistochemistry. Secretion ameloblasts and maturation ameloblasts, including both ruffle-ended and smooth-ended cells, were labeled with anti-SERCA2 antibodies, with maturation ameloblasts showing stronger binding than secretion ameloblasts. The pattern of labeling was cytoplasmic and diffuse. Papillary layer cells were not labeled with anti-SERCA2 antibodies. These results suggest that the SERCA2 in ameloblasts is intimately involved in mineralization during amelogenesis.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	0044-5991 1347-5800
DOI:	10.1267/ahc.36.331