Patented technologies for schistosomiasis control and prevention filed by Chinese applicants

• Published in: Infectious diseases of poverty Vol. 10; no. 1; pp. 1 - 84
• Main Authors: Xiong, Yan-Hong, Xu, Xue-Nian, Zheng, Bin
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 12-06-2021; BioMed Central; BMC
• Subjects: Acids; Antibodies; Antiparasitic agents; Cancer; Chemotherapy; Control and prevention; Control systems; Developmental biology; Intellectual property; Livestock; Medicine, Botanic; Medicine, Herbal; Mollusks; Online databases; Patent analysis; Plant extracts; Prevention; Proteins; R&D; Research & development; RNA; Schistosomiasis; Serology; Technology; Trends; China
• ISSN: 2049-9957; 2095-5162; 2049-9957
• DOI: 10.1186/s40249-021-00869-6

Background Many valuable and productive patented technologies have been developed to control schistosomiasis in China in the past 70 years. We conducted a research to analyse patented technologies for schistosomiasis control and prevention filed by Chinese applicants for determining the future patent layout. Methods The patent databases of China National Intellectual Property Administration and Baiten were comprehensively searched, and patented technologies for schistosomiasis control and prevention, published between January 1950 and December 2020 filed by Chinese applicants were sorted on 30 December 2020. The patent types, technical fields, and patent development trends were analysed using patent indexing. Results There are 184 valid schistosomiasis control technology patents, among them 128 invention patents. The patents related to schistosomiasis control and prevention technology have gone through the germination, growth, and maturity stages. These phases correspond with three phases in schistosomiasis control in China. The main technical aspects were fundamental research (n = 37), detection (n = 13), chemotherapy (n = 61), and armamentarium/devices (n = 73), of which the number of patents for detection for diagnosis was smaller. The top three specialised technical fields for patents subgroups, focusing on antiparasitic agents, DNA or RNA, vectors and medicines, of which schistosomicides are the major dominant subgroup. Conclusions We recommend that technologies to be patented for schistosomiasis control and prevention be focused on detection, preliminary studies for molecular detection methods should be significantly enhanced, and patent layout must be performed, which will, in turn, promote accuracy of early diagnosis, not only in humans but also in livestock. It is necessary to develop more anti-schistosomal drugs safely and effectively, exceptionally eco-friendly molluscicides and herbal extracts anti-schistosomes, improve treatment, develop vaccines for use in humans. Graphic abstract Keywords: Schistosomiasis, Patent analysis, Control and prevention, Technology