Evaluation of the Photoactivation Effect of 3% Hydrogen Peroxide in the Disinfection of Dental Implants: In Vitro Study

• Published in: Biomedicines Vol. 11; no. 4; p. 1002
• Main Authors: Katalinić, Ivan, Smojver, Igor, Morelato, Luka, Vuletić, Marko, Budimir, Ana, Gabrić, Dragana
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 24-03-2023; MDPI
• Subjects: 3% hydrogen peroxide; Analysis; Antibiotics; Biofilms; Care and treatment; Chlorhexidine; Debridement; Dental implants; Dental prosthetics; diode laser; Disinfection; Hydrogen peroxide; Implant dentures; Infection control; Lasers; Microorganisms; Mucositis; Pathogens; periimplantitis therapy; Photoactivation; Physiology; Staphylococcus aureus; Staphylococcus aureus infections; Statistical analysis; Tetracycline; Tetracyclines; Titanium; Croatia; United States > US; diode laser; photoactivation; 3% hydrogen peroxide; periimplantitis therapy
• ISSN: 2227-9059; 2227-9059
• DOI: 10.3390/biomedicines11041002

Photoactivation of 3% hydrogen peroxide with a 445 nm diode laser represents a relatively new, insufficiently researched antimicrobial method in the treatment of peri-implantitis. The purpose of this work is to evaluate the effect of photoactivation of 3% hydrogen peroxide with a 445 nm diode laser, and to compare the obtained results with 0.2% chlorhexidine treatment and 3% hydrogen peroxide treatment without photoactivation, in vitro, on the surface of dental implants contaminated with
and
biofilms. Previously, 80 infected titanium implants with
and
cultures were divided into four groups: G1-negative control (no treatment), G2-positive control (0.2% chlorhexidine), G3 (3% hydrogen peroxide), and G4 (photoactivated 3% hydrogen peroxide). The number of viable microbes in each sample was determined by the colony forming unit (CFU) count. The results were statistically processed and analyzed, showing a statistically significant difference across all groups compared to the negative control (G1), and the absence of a statistically significant difference between groups G1-G3. The new antimicrobial treatment, according to the results, could be worthy of further analysis and research.