Two-Level Micro-to-Nanoscale Hierarchical TiO₂ Nanolayers on Titanium Surface

• Published in: Materials Vol. 9; no. 12; p. 1010
• Main Authors: Zemtsova, Elena G, Arbenin, Andrei Yu, Valiev, Ruslan Z, Orekhov, Evgeny V, Semenov, Valentin G, Smirnov, Vladimir M
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 13-12-2016; MDPI
• Subjects: Adhesion; Biocompatibility; Biological activity; Bones; cell state; cracks; Dentistry; dip coating; Dip coatings; Microscopy; Morphology; Nanostructure; Nanostructured materials; Networks; Orthopedics; osteoblasts; roughness; shock drying; sol-gel; Surgical implants; TiO2 nanolayers; Titanium; Titanium dioxide; Transplants & implants; Russia; TiO2 nanolayers; dip coating; roughness; shock drying; cracks; osteoblasts; cell state; sol-gel
• ISSN: 1996-1944; 1996-1944
• DOI: 10.3390/ma9121010

Joint replacement is being actively developed within modern orthopedics. One novel material providing fast implantation is bioactive coatings. The synthesis of targeted nanocoatings on metallic nanotitanium surface is reported in this paper. TiO₂-based micro- and nanocoatings were produced by sol-gel synthesis using dip-coating technology with subsequent fast (shock) drying in hot plate mode at 400 °C. As a result of shock drying, the two-level hierarchical TiO₂ nanolayer on the nanotitanium was obtained. This two-level hierarchy includes nanorelief of porous xerogel and microrelief of the micron-sized "defect" network (a crack network). The thickness of TiO₂ nanolayers was controlled by repeating dip-coating process the necessary number of times after the first layer deposition. The state of the MS3T3-E1 osteoblast cell line (young cells that form bone tissue) on the two-level hierarchical surface has been studied. Particularly, adhesion character, adhesion time and morphology have been studied. The reported results may serve the starting point for the development of novel bioactive coatings for bone and teeth implants.