Diagnosis and Treatment of Fungal Infections in Lung Transplant Recipients

Fungal infections are a significant source of morbidity in the lung transplant population via direct allograft damage and predisposing patients to the development of chronic lung allograft dysfunction. Prompt diagnosis and treatment are imperative to limit allograft damage. This review article discu...

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Bibliographic Details
Published in:	Pathogens (Basel) Vol. 12; no. 5; p. 694
Main Authors:	Escamilla, Jesus E, January, Spenser E, Vazquez Guillamet, Rodrigo
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 10-05-2023 MDPI
Subjects:	Allografts antifungals Antigens Damage Diagnosis Disease prevention Drug therapy Fungal infections Fungi Ischemia Lung diseases, Fungal lung transplant Lung transplantation Lung transplants Lungs Microorganisms Morbidity Organ transplant recipients Review Risk factors Transplantation United States lung transplant antifungals fungal infections
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Summary:	Fungal infections are a significant source of morbidity in the lung transplant population via direct allograft damage and predisposing patients to the development of chronic lung allograft dysfunction. Prompt diagnosis and treatment are imperative to limit allograft damage. This review article discusses incidence, risk factors, and symptoms with a specific focus on diagnostic and treatment strategies in the lung transplant population for fungal infections caused by , , , , , , , and . Evidence for the use of newer triazole and inhaled antifungals to treat isolated pulmonary fungal infections in lung transplant recipients is also discussed.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 These authors contributed equally to this work.
ISSN:	2076-0817 2076-0817
DOI:	10.3390/pathogens12050694