Terminal steps in the biosynthesis of herbicidins, nucleoside antibiotics

Terminal steps in the biosynthesis of herbicidins, nucleoside antibiotics

The biosynthetic relationship of the herbicidins produced by Streptomyces saganonensis was studied with blocked mutants by means of a bioconversion method using growing and resting cells. It is proposed that the biosynthetic sequence for herbicidins is; herbicidin G---herbicidin F---herbicidin A. Bo...

Full description

Saved in:
Bibliographic Details
Published in:Journal of antibiotics Vol. 36; no. 1; p. 30
Main Authors: Yoshikawa, H, Takiguchi, Y, Terao, M
Format: Journal Article
Language:English
Published: Japan 01-01-1983
Subjects:
Anti-Bacterial Agents - biosynthesis
Biotransformation
Fermentation
Purine Nucleosides - biosynthesis
Streptomyces - metabolism
Time Factors
Online Access:Get more information
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The biosynthetic relationship of the herbicidins produced by Streptomyces saganonensis was studied with blocked mutants by means of a bioconversion method using growing and resting cells. It is proposed that the biosynthetic sequence for herbicidins is; herbicidin G---herbicidin F---herbicidin A. Both herbicidins A and F were converted to herbicidin B by non-enzymatic reactions. Herbicidin G was also converted to herbicidin C non-enzymatically.
ISSN:0021-8820
DOI:10.7164/antibiotics.36.30