The outdoor air pollution and brain health workshop

• Published in: Neurotoxicology (Park Forest South) Vol. 33; no. 5; pp. 972 - 984
• Main Authors: Block, Michelle L., Elder, Alison, Auten, Richard L., Bilbo, Staci D., Chen, Honglei, Chen, Jiu-Chiuan, Cory-Slechta, Deborah A., Costa, Daniel, Diaz-Sanchez, David, Dorman, David C., Gold, Diane R., Gray, Kimberly, Jeng, Hueiwang Anna, Kaufman, Joel D., Kleinman, Michael T., Kirshner, Annette, Lawler, Cindy, Miller, David S., Nadadur, Srikanth S., Ritz, Beate, Semmens, Erin O., Tonelli, Leonardo H., Veronesi, Bellina, Wright, Robert O., Wright, Rosalind J.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01-10-2012; Elsevier
• Subjects: Air; Air Pollutants - poisoning; Air pollution; Air Pollution - adverse effects; Behavior; Biological and medical sciences; Brain; Brain - pathology; Cardiovascular Diseases - chemically induced; Cardiovascular Diseases - pathology; Central nervous system; Disease Susceptibility; Encephalitis - etiology; Encephalitis - pathology; Environmental pollutants toxicology; Epidemiology; Humans; Lung Diseases - chemically induced; Lung Diseases - pathology; Medical sciences; Neuroinflammation; Neurotoxicity; Neurotoxicity Syndromes - epidemiology; Neurotoxicity Syndromes - etiology; Neurotoxicity Syndromes - pathology; Ozone; Particulate matter; Susceptibility; Toxicology; VOCs; Brain; AD; BBB; Susceptibility; Central nervous system; CNS; Ozone; Neuroinflammation; NIH; CO; TNF; Epidemiology; UF; Neurotoxicity; PD; Particulate matter; NIEHS; PAHs; Air pollution; TLR; CYP; Behavior; PM; Congress; Human; Nervous system diseases; Toxicity; Encephalon; Suspended particle; Workshop; Public health
• ISSN: 0161-813X; 1872-9711
• DOI: 10.1016/j.neuro.2012.08.014

Accumulating evidence suggests that outdoor air pollution may have a significant impact on central nervous system (CNS) health and disease. To address this issue, the National Institute of Environmental Health Sciences/National Institute of Health convened a panel of research scientists that was assigned the task of identifying research gaps and priority goals essential for advancing this growing field and addressing an emerging human health concern. Here, we review recent findings that have established the effects of inhaled air pollutants in the brain, explore the potential mechanisms driving these phenomena, and discuss the recommended research priorities/approaches that were identified by the panel.