Small Interfering RNA Screens Reveal Enhanced Cisplatin Cytotoxicity in Tumor Cells Having both BRCA Network and TP53 Disruptions

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Published in:	Molecular and Cellular Biology Vol. 26; no. 24; pp. 9377 - 9386
Main Authors:	Bartz, Steven R., Zhang, Zhan, Burchard, Julja, Imakura, Maki, Martin, Melissa, Palmieri, Anthony, Needham, Rachel, Guo, Jie, Gordon, Marcia, Chung, Namjin, Warrener, Paul, Jackson, Aimee L., Carleton, Michael, Oatley, Melissa, Locco, Louis, Santini, Francesca, Smith, Todd, Kunapuli, Priya, Ferrer, Marc, Strulovici, Berta, Friend, Stephen H., Linsley, Peter S.
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 01-12-2006 Taylor & Francis
Subjects:	Antineoplastic Agents - toxicity BRCA1 Protein - antagonists & inhibitors BRCA1 Protein - metabolism BRCA2 Protein - antagonists & inhibitors BRCA2 Protein - metabolism Cell Line, Tumor Cisplatin - toxicity Drug Resistance, Neoplasm - genetics HeLa Cells Humans Neoplasms - drug therapy Neoplasms - genetics Neoplasms - pathology RNA, Small Interfering - physiology Tumor Suppressor Protein p53 - antagonists & inhibitors Tumor Suppressor Protein p53 - biosynthesis Tumor Suppressor Protein p53 - deficiency
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Summary:	Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue MCB About MCB Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy MCB RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0270-7306 Online ISSN: 1098-5549 Copyright © 2014 by the American Society for Microbiology. For an alternate route to MCB .asm.org, visit: MCB
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Corresponding author. Mailing address: Rosetta Inpharmatics, LLC, 401 Terry Ave N., Seattle, WA 98109. Phone: (206) 802-6451. Fax: (206) 802-6388. E-mail: steven_bartz@merck.com. These authors made equal contributions to the work.
ISSN:	0270-7306 1098-5549 1098-5549
DOI:	10.1128/MCB.01229-06