Physiopathological effects of Escherichia coli O157:H7 inoculation in weaned calves fed with colostrum containing antibodies to EspB and Intimin

• Published in: Vaccine Vol. 32; no. 30; pp. 3823 - 3829
• Main Authors: Rabinovitz, B.C, Vilte, D.A, Larzábal, M, Abdala, A, Galarza, R, Zotta, E, Ibarra, C, Mercado, E.C, Cataldi, A
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 24-06-2014; Elsevier
• Subjects: Adhesins, Bacterial - immunology; Allergy and Immunology; Animals; Antibodies, Bacterial - blood; Antibodies, Bacterial - immunology; Applied microbiology; Bacterial Outer Membrane Proteins - immunology; Bacterial Shedding; Bacteriology; Biological and medical sciences; Calves; Cattle; Cattle Diseases - immunology; Cattle Diseases - prevention & control; Colostrum; Colostrum - immunology; EHEC O157:H7; Escherichia coli; Escherichia coli Infections - immunology; Escherichia coli Infections - prevention & control; Escherichia coli Infections - veterinary; Escherichia coli O157; Escherichia coli Proteins - immunology; Escherichia coli Vaccines - administration & dosage; Feces - microbiology; Female; Fundamental and applied biological sciences. Psychology; IgG; Immunity, Maternally-Acquired; Immunity, Mucosal; Immunoglobulin G - blood; Immunoglobulin G - immunology; Microbiology; Miscellaneous; Pregnancy; Vaccine; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); IgG; Calves; EHEC O157:H7; Vaccine; Colostrum; Bovine; Antibody; Colibacillosis; Escherichia coli; Infection; Vertebrata; Mammalia; Weaned animal; Bacteriosis; Bacteria; Artiodactyla; Veterinary; Ungulata; Enterobacteriaceae
• ISSN: 0264-410X; 1873-2518
• DOI: 10.1016/j.vaccine.2014.04.073

Highlights • Attempt of colonization control of EHEC in bovines by passive immunization. • Transfer of colostrum antibodies to EspB and Intimin to young calves. • Detection of specific antibodies in intestinal segments. • Need of high titers of specific antibodies to achieve protection.