Effects of chronic peripheral olfactory loss on functional brain networks

Highlights • Olfactory loss affects functional networks in anosmic patients. • Functional connectivity decrease was determined even beyond the olfactory network. • Anosmic patients still have a functional olfactory network activated by sniffing.

Saved in:

Bibliographic Details
Published in:	Neuroscience Vol. 310; pp. 589 - 599
Main Authors:	Kollndorfer, K, Jakab, A, Mueller, C.A, Trattnig, S, Schöpf, V
Format:	Journal Article
Language:	English
Published:	United States Elsevier Ltd 03-12-2015
Subjects:	Adult anosmia Brain Mapping Chronic Disease Female functional connectivity Humans Magnetic Resonance Imaging Male Middle Aged Neurology Odorants olfaction Olfaction Disorders - etiology Olfaction Disorders - physiopathology Olfactory Pathways - physiopathology Olfactory Perception - physiology piriform cortex Respiratory Tract Infections - complications sniffing general linear models independent components piriform cortex GLM Threshold-Detection–Identification olfaction functional connectivity analysis GIFT SD independent component analysis Network-Based Statistics anosmia ICs TDI NBS ROIs FCA ICA regions of interest Group ICA for fMRI Toolbox functional connectivity echo-planar imaging sniffing EPI standard deviation
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Highlights • Olfactory loss affects functional networks in anosmic patients. • Functional connectivity decrease was determined even beyond the olfactory network. • Anosmic patients still have a functional olfactory network activated by sniffing.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2015.09.045