Non-Hodgkin's lymphoma: A review

• Published in: Journal of family medicine and primary care Vol. 9; no. 4; pp. 1834 - 1840
• Main Authors: Singh, Rohit, Shaik, Shabana, Negi, Bhupender, Rajguru, Jagadish, Patil, Pankaj, Parihar, Anuj, Sharma, Uma
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01-04-2020; Medknow Publications and Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: cell; lymphomas; non hodgkin's lymphoma; Non-Hodgkin's lymphomas; Review; lymphomas; Cell; Non Hodgkin's lymphoma
• ISSN: 2249-4863; 2278-7135
• DOI: 10.4103/jfmpc.jfmpc_1037_19

Lymphomas constitute the third most common neoplasm in head and neck region arising from the lymphoreticular system. Malignant lymphomas are divided into Hodgkin's disease and non-Hodgkin's lymphoma (NHL). NHL comprises approximately 5% of head and neck malignancies and displays a wide range of appearances comparable with Hodgkin's disease. Hodgkin's and non-Hodgkin's lymphomas are seen in the head and neck region, but extranodal disease, with or without lymph node involvement, is more common among NHL patients. Extranodal involvement includes the areas such as Waldeyer's ring (i.e., the tonsils, pharynx, and base of the tongue), salivary glands, orbit, paranasal sinuses, and thyroid glands. There are several classification systems for categorizing NHL out of which WHO classification for lymphoid neoplasms is mostly followed. This review describes the pathogenesis of NHL and explains some of the important NHL (Marginal zone B-cell Lymphoma, follicular lymphoma, mantle cell lymphoma).