HIV-Specific T Cell Responses Are Highly Stable on Antiretroviral Therapy

HIV infection induces a robust T cell response that is sustained by high viremia, but falls following the onset of antiretroviral therapy (ART). Relatively little has been reported on the subsequent stability of the HIV-specific T cell response in individuals on durable therapy. Such data are critic...

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Bibliographic Details
Published in:	Molecular therapy. Methods & clinical development Vol. 15; pp. 9 - 17
Main Authors:	Xu, Yinyan, Trumble, Ilana M., Warren, Joanna A., Clutton, Genevieve, Abad-Fernandez, Maria, Kirchnerr, Jennifer, Adimora, Adaora A., Deeks, Steven G., Margolis, David M., Kuruc, JoAnn D., Gay, Cynthia L., Archin, Nancie M., Mollan, Katie R., Hudgens, Michael, Goonetilleke, Nilu
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 13-12-2019 Elsevier Limited American Society of Gene & Cell Therapy Elsevier
Subjects:	Acquired immune deficiency syndrome Age AIDS Antiretroviral drugs Antiretroviral therapy CD8 Cell size Clinical trials Drug therapy Enzyme-linked immunosorbent assay Ethnicity Hispanic Americans HIV Human immunodeficiency virus Immunotherapy Infections Interferon Leukocytes (mononuclear) Lymphocytes Lymphocytes T Peptides Peripheral blood mononuclear cells Proteins T cell Vaccines Viremia HIV T cell CD8 immunotherapy
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