Bilateral pulmonary nodules as a manifestation of primary pulmonary T-cell lymphoma

• Published in: International journal of hematology Vol. 90; no. 2; pp. 153 - 156
• Main Authors: Bernabeu Mora, Roberto, Sánchez Nieto, Juan Miguel, Nieto Olivares, Andrés
• Format: Journal Article
• Language: English
• Published: Tokyo Springer Japan 01-09-2009; Springer; Springer Nature B.V
• Subjects: Aged; Biological and medical sciences; Biopsy; Case Report; Diagnosis, Differential; Fatal Outcome; Female; Hematologic and hematopoietic diseases; Hematology; Humans; Lung - diagnostic imaging; Lung - pathology; Lung Neoplasms - diagnostic imaging; Lung Neoplasms - pathology; Lymphoma, T-Cell - diagnostic imaging; Lymphoma, T-Cell - pathology; Medical sciences; Medicine; Medicine & Public Health; Multiple Pulmonary Nodules - diagnostic imaging; Multiple Pulmonary Nodules - pathology; Oncology; Tomography, X-Ray Computed; Bilateral pulmonary nodules; Primary pulmonary lymphoma; T-cell lymphoma; Hematology; T lymphoma; Lung; Primary; Bilateral; Lymphoid neoplasm; Respiratory system; Nodule
• ISSN: 0925-5710; 1865-3774
• DOI: 10.1007/s12185-009-0372-8

Primary pulmonary lymphoma (PPL) is an uncommon pathology and is usually of the B-cell type, originating in lymphoid tissue associated with the bronchial mucosa (MALT/BALT lymphoma). Very few cases of T-cell PPL, the majority diagnosed by open lung biopsy, have been described in medical literature. We report a case of an immunocompetent patient with fever and bilateral pulmonary nodules, diagnosed with T-cell PPL by transbronchial biopsy. The patient’s condition deteriorated and she responded poorly to chemotherapy. PPL should be included in the differential diagnosis of patients with fever and bilateral pulmonary nodules.