Clinical utility of three-dimensional SPECT/CT imaging as a guide for the resection of medication-related osteonecrosis of the jaw

• Published in: International journal of oral and maxillofacial surgery Vol. 44; no. 9; pp. 1106 - 1109
• Main Authors: Miyashita, H, Shiba, H, Kawana, H, Nakahara, T
• Format: Journal Article
• Language: English
• Published: Denmark Elsevier Ltd 01-09-2015
• Subjects: Bisphosphonate-Associated Osteonecrosis of the Jaw - diagnostic imaging; Bisphosphonate-Associated Osteonecrosis of the Jaw - surgery; dental implantation; Dentistry; Female; Humans; Imaging, Three-Dimensional; medication-related osteonecrosis of the jaw; Middle Aged; Multimodal Imaging; quality of life; Radiopharmaceuticals; Surgery; three-dimensional SPECT/CT; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; two-stage operation; medication-related osteonecrosis of the jaw; quality of life; two-stage operation; three-dimensional SPECT/CT; dental implantation
• ISSN: 0901-5027; 1399-0020
• DOI: 10.1016/j.ijom.2015.05.002

Abstract In recent years, proactive surgical treatment has been reported to be effective for medication-related osteonecrosis of the jaw (MRONJ). However, an uncertain resection entails the risk of recurrence, whereas an extensive surgical procedure may lead to a marked reduction in quality of life as a result of reduced masticatory function and poor cosmesis. Therefore, radiological assessment can be helpful to accurately localize MRONJ before surgery. The integrated single-photon emission computed tomography and computed tomography system (SPECT/CT) allows oral and maxillofacial surgeons to identify an area of MRONJ, especially when three-dimensional (3D) SPECT and CT fusion images are offered. A patient for whom 3D SPECT and CT image fusion (as developed in the radiology department of the study institution) contributed to determining the extent of the lesion, thereby leading to a favourable patient prognosis, is reported herein. There was exact correlation between the histological and radiological results.