Statin and the risk of hepatocellular carcinoma and death in a hospital-based hepatitis B-infected population: A propensity score landmark analysis

• Published in: Journal of hepatology Vol. 63; no. 5; pp. 1190 - 1197
• Main Authors: Hsiang, John Chen, Wong, Grace Lai-Hung, Tse, Yee-Kit, Wong, Vincent Wai-Sun, Yip, Terry Cheuk-Fung, Chan, Henry Lik-Yuen
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-11-2015
• Subjects: Aged; Alanine aminotransferase; Albumin; Carcinoma, Hepatocellular - epidemiology; Carcinoma, Hepatocellular - etiology; Carcinoma, Hepatocellular - prevention & control; Cause of Death - trends; Cross Infection; Death; Female; Follow-Up Studies; Gastroenterology and Hepatology; Hepatitis B; Hepatitis B, Chronic - complications; Hepatitis B, Chronic - drug therapy; Hepatitis B, Chronic - epidemiology; Hepatocellular carcinoma; Hong Kong - epidemiology; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Incidence; Inpatients; Landmark analysis; Liver Neoplasms - epidemiology; Liver Neoplasms - etiology; Liver Neoplasms - prevention & control; Male; Middle Aged; Nucleos(t)ide analogue; Prognosis; Propensity Score; Prospective Studies; Retrospective Studies; Statin; Survival Rate - trends; PS; DDD; hepatitis B virus; alanine aminotransferase; ALT; DM; HR; interquartile range; SD; 3-hydroxy-3-methylglutaryl CoA; hepatitis C virus; type 2 diabetes mellitus; Landmark analysis; HBV; hepatocellular carcinoma; nucleos(t)ide analogue; daily defined doses; CI; Albumin; HCC; HMG-CoA; IQR; Statin; ATE; NA; HIV; Hospital Authority; hazard ratio; human immunodeficiency virus; HA; Death; confidence interval; HCV; average treatment effect; standard deviation; propensity score; Hepatitis B; Hepatocellular carcinoma; Nucleos(t)ide analogue; Alanine aminotransferase
• ISSN: 0168-8278; 1600-0641
• DOI: 10.1016/j.jhep.2015.07.009

Graphical abstract