Miniaturized Microfluidic Electrochemical Biosensors Powered by Enzymatic Biofuel Cell

• Published in: Biosensors (Basel) Vol. 13; no. 2; p. 175
• Main Authors: Wang, Linlin, Zhu, Wenlei, Zhang, Jianrong, Zhu, Jun-Jie
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 22-01-2023; MDPI
• Subjects: Antigens; Biochemical fuel cells; Biodiesel fuels; Biofuels; Biosensors; Dehydrogenases; Electrochemical apparatus; electrochemical biosensor; Electrochemistry; Electrodes; enzymatic biofuel cell; Enzymes; Fuel cells; Glucose; Medical equipment; microfluidic technology; Microfluidics; Oxidation; Portability; R&D; Research & development; Review; Screen printing; self-powered biosensor; Sensors; Signal generators; China; enzymatic biofuel cell; microfluidic technology; self-powered biosensor; electrochemical biosensor; screen-printing
• ISSN: 2079-6374; 2079-6374
• DOI: 10.3390/bios13020175

Electrochemical biosensors, in which enzymatic biofuel cells simultaneously work as energy power and signal generators, have become a research hotspot. They display the merits of power self-support, a simplified structure, in vivo operational feasibility, online and timely monitoring, etc. Since the concept of enzymatic biofuel cell-powered biosensors (EBFC-SPBs) was first proposed, its applications in health monitoring have scored tremendous achievements. However, the creation and practical application of portable EBFC-SPBs are still impeded by the difficulty in their miniaturization. In recent years, the booming microfluidic technology has powerfully pushed forward the progress made in miniaturized and portable EBFC-SPBs. This brief review recalls and summarizes the achievements and progress made in miniaturized EBFC-SPBs. In addition, we also discuss the advantages and challenges that microfluidic and screen-printing technologies provide to wearable and disposable EBFC-SPBs.