A case of catecholaminergic polymorphic ventricular tachycardia masquerading as an intractable seizure

• Published in: Annals of pediatric cardiology Vol. 13; no. 2; pp. 141 - 143
• Main Authors: Shabanian, Reza, Ahani, Manizheh, Zandiyeh, Shima, Nikdoost, Aliyeh, Dadkhah, Minoo, Asbagh, Parvin, Badv, Reza
• Format: Journal Article
• Language: English
• Published: Mumbai Wolters Kluwer India Pvt. Ltd 01-05-2020; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: Arrhythmia; Cardiac arrhythmia; Cardiopulmonary resuscitation; Case Report; catecholaminergic polymorphic ventricular tachycardia; channelopathy; Convulsions & seizures; Cyanosis; Drug resistance; Electric countershock; Emergency medical services; Epilepsy; Esmolol; Genetic aspects; intractable seizure; Mutation; Nadolol; Patients; Pediatric cardiology; Seizures (Medicine); Tachycardia; Ventricular tachycardia; catecholaminergic polymorphic ventricular tachycardia; Arrhythmia; channelopathy; intractable seizure
• ISSN: 0974-2069; 0974-5149
• DOI: 10.4103/apc.APC_73_19

A 5-year-old boy with the history of intractable seizure for the past 2 years was transferred to the emergency room for cardiopulmonary resuscitation because of the prolonged seizure and profound cyanosis. He was intubated and resuscitated by cardioversion for a bizarre shape ventricular tachycardia (VT). After noxious stimulation, he showed multiple polymorphic ventricular premature beats that were followed by a bidirectional VT in favor of catecholaminergic polymorphic VT. The genetic assessment was positive for CASQ2 mutation. In the follow-up, the arrhythmia was controlled by nadolol, however with a prominent neurological sequela.