Two cases of Osteoarticular Mucor menace: A diagnostic and management conundrum

• Published in: Drug Discoveries & Therapeutics Vol. 12; no. 6; pp. 374 - 378
• Main Authors: Bhatt, Manasvini, Soneja, Manish, Fazal, Farhan, Vyas, Surabhi, Kumar, Prabhat, Jorwal, Pankaj, Raj, Upendra, Sachdev, Janya, Singh, Gagandeep, Xess, Immaculata, Alam, Shah, Biswas, Ashutosh
• Format: Journal Article
• Language: English
• Published: Japan International Research and Cooperation Association for Bio & Socio-Sciences Advancement 31-12-2018
• Subjects: Adult; Amputation; Antifungal Agents - therapeutic use; bone mucormycosis; Burns - microbiology; Burns - surgery; chronic granulomatous disease; Debridement - adverse effects; Disease Management; Granulomatous Disease, Chronic - microbiology; Humans; Lower Extremity - microbiology; Lower Extremity - surgery; Male; Mucormycosis; Mucormycosis - diagnosis; Mucormycosis - etiology; Mucormycosis - therapy; Pelvic Bones - microbiology; Pelvic Bones - surgery; Young Adult; Mucormycosis; bone mucormycosis; chronic granulomatous disease
• ISSN: 1881-7831; 1881-784X
• DOI: 10.5582/ddt.2018.01064

Mucormycosis is an uncommon aggressive fungal infection usually seen in immunocompromised hosts or patients with burns and trauma. The common presentations include rhino-orbital-cerebral and pulmonary involvement. Osteoarticular involvement is a rare presentation of this disease. We present two cases of osteoarticular mucormycosis of pelvis and long bones of the lower limb, one in a patient with burn injury and other one in a patient with chronic granulomatous disease, hitherto a rarely reported association. Delayed diagnosis in a setting where tuberculosis is a common cause of chronic osteomyelitis, challenges in medical and surgical management of these patients are discussed in this report.