Primary cutaneous histoplasmosis mimicking basal cell carcinoma of the eyelid: A case report and review of literature

We present the case of a 46 years old gentleman with longstanding ulcerative lesion of the right upper eyelid. Biopsy of the lesion revealed intracellular periodic acid-Schiff positive round to oval organisms with a surrounding clear halo suggestive of histoplasmosis. Histoplasma capsulatum specific...

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Bibliographic Details
Published in:	Indian journal of pathology & microbiology Vol. 59; no. 2; pp. 227 - 228
Main Authors:	Radhakrishnan, Santhi, Adulkar, Namrata, Kim, Usha
Format:	Journal Article
Language:	English
Published:	India Wolters Kluwer - Medknow Publications 01-04-2016 Medknow Publications and Media Pvt. Ltd Wolters Kluwer Medknow Publications
Subjects:	Basal cell carcinoma Care and treatment Case studies Diagnosis Eyelid biopsy, eyelid malignancy, primary cutaneous histoplasmosis Eyelid diseases Histoplasma capsulatum Histoplasmosis primary cutaneous histoplasmosis eyelid malignancy Eyelid biopsy
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Summary:	We present the case of a 46 years old gentleman with longstanding ulcerative lesion of the right upper eyelid. Biopsy of the lesion revealed intracellular periodic acid-Schiff positive round to oval organisms with a surrounding clear halo suggestive of histoplasmosis. Histoplasma capsulatum specific polymerase chain reaction was positive. The patient was treated with oral antifungals and showed a prompt response to treatment. We report this rare case of primary cutaneous histoplasmosis of the eyelid in an otherwise healthy adult patient.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0377-4929 0974-5130
DOI:	10.4103/0377-4929.182017