Effect of different contents of extruded linseed in the sow diet on piglet fatty acid composition and hepatic desaturase expression during the post-natal period

• Published in: Animal (Cambridge, England) Vol. 7; no. 10; pp. 1671 - 1680
• Main Authors: de Quelen, F., Boudry, G., Mourot, J.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01-10-2013; Elsevier Limited; Published by Elsevier (since 2021) / Cambridge University Press (until 2020); Elsevier
• Subjects: Animal Feed - analysis; Animal Nutritional Physiological Phenomena; Animals; brain; diet; Diet - veterinary; fatty acid composition; Fatty Acid Desaturases - genetics; Fatty Acid Desaturases - metabolism; Fatty Acids - chemistry; Fatty Acids - metabolism; Female; gene expression; Gene Expression Regulation, Developmental - physiology; Gene Expression Regulation, Enzymologic - physiology; growth and development; lactation; Life Sciences; linseed; liver; Liver - enzymology; maternal nutrition; Maternal Nutritional Physiological Phenomena; messenger RNA; milk; n-3 polyunsaturated fatty acid, sow diet, piglet, fatty acid composition, desaturase gene expression; omega-3 fatty acids; Physiology and functional biology of systems; piglets; polyunsaturated fatty acids; postpartum period; pregnancy; sow milk; sows; suckling; sunflower oil; Swine - physiology; tissues; n-3 polyunsaturated fatty acid, sow diet, piglet, fatty acid composition, desaturase gene expression; piglet; sow diet; desaturase gene expression; fatty acid composition; n-3 polyunsaturated fatty acid
• ISSN: 1751-7311; 1751-732X; 1751-732X
• DOI: 10.1017/S1751731113001067

n-3 polyunsaturated fatty acids (n-3 PUFA) contribute to the normal growth and development of numerous organs in the piglet. The fatty acid composition of piglet tissues is linked to the fatty acid composition of sow milk and, consequently, to the composition of sow diet during the gestation and lactation period. In this study, we investigated the impact of different contents of extruded linseed in the sow diet on the fatty acid composition and desaturase gene expression of piglets. Sows received a diet containing either sunflower oil (low 18:3n-3 with 18:3n-3 representing 3% of total fatty acids) or a mixture of extruded linseed and sunflower oil (medium 18:3n-3 with 9% of 18:3n-3) or extruded linseed (high 18:3n-3 with 27% of 18:3n-3) during gestation and lactation. Fatty acid composition was evaluated on sow milk and on different piglet tissues at days 0, 7, 14, 21 and 28. The postnatal evolution of delta5 (D5D) and delta6 (D6D) desaturase mRNA expression was also measured in the liver of low 18:3n-3 and high 18:3n-3 piglets. The milk of high 18:3n-3 sows had higher proportions of n-3PUFA than that of low 18:3n-3 and medium 18:3n-3 sows. Piglets suckling the high 18:3n-3 sows had greater proportions of 18:3n-3, 20:5n-3, 22:5n-3 and 22:6n-3 in the liver, and of 22:5n-3 and 22:6n-3 in the brain than low 18:3n-3 and medium 18:3n-3 piglets. D5D and D6D mRNA expressions in piglet liver were not affected by the maternal diet at any age. In conclusion, extruded linseed in the sow diet modifies the n-3PUFA status of piglets during the postnatal period. However, a minimal content of 18:3n-3 in the sow diet is necessary to increase the n-3PUFA level in piglet liver and brain. Moreover, modifications in the n-3PUFA fatty acid composition of piglet tissue seem linked to the availability of 18:3n-3 in maternal milk and not to desaturase enzyme expression.