Fixation-related saccadic inhibition in free viewing in response to stimulus saliency

• Published in: Scientific reports Vol. 12; no. 1; p. 6619
• Main Authors: Kadosh, Oren, Bonneh, Yoram S.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 22-04-2022; Nature Publishing Group; Nature Portfolio
• Subjects: 631/378/2613; 631/378/2617/1795; Attention - physiology; Data analysis; Experiments; Eye movements; Fixation, Ocular; Frequency dependence; Humanities and Social Sciences; Humans; Hypotheses; Inhibition, Psychological; Latency; Males; multidisciplinary; Photic Stimulation; Saccades; Saccadic eye movements; Science; Science (multidisciplinary); Velocity; Vision, Ocular; Visual Perception - physiology; Visual stimuli
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-10605-1

Microsaccades that occur during fixation were studied extensively in response to transient stimuli, showing a typical inhibition (Oculomotor Inhibition, OMI), and a later release with a latency that depends on stimulus saliency, attention, and expectations. Here, we investigated the hypothesis that in free viewing every saccade provides a new transient stimulation that should result in a stimulus-dependent OMI like a flashed presentation during fixation. Participants (N = 16) freely inspected static displays of randomly oriented Gabor texture images, with varied contrast and spatial frequency (SF) for periods of 10 s each. Eye tracking recordings were divided into epochs triggered by saccade landing (> 1 dva), and microsaccade latency relative to fixation onset was computed (msRT). We found that the msRT in free viewing was shorter for more salient stimuli (higher contrast or lower SF), as previously found for flashed stimuli. It increased with saccade size and decreased across successive saccades, but only for higher contrast, suggesting contrast-dependent repetition enhancement in free viewing. Our results indicate that visual stimulus-dependent inhibition of microsaccades also applies to free viewing. These findings are in agreement with the similarity found between event-related and fixation-related potentials and open the way for studies combining both approaches to study natural vision.