Biogenic Synthesis, Characterization and Antibacterial Potential Evaluation of Copper Oxide Nanoparticles Against Escherichia coli

• Published in: Nanoscale research letters Vol. 16; no. 1; pp. 148 - 13
• Main Authors: Ali, Mohsin, Ijaz, Muhammad, Ikram, Muhammad, Ul-Hamid, Anwar, Avais, Muhammad, Anjum, Aftab Ahmad
• Format: Journal Article
• Language: English
• Published: New York Springer US 20-09-2021; Springer Nature B.V; SpringerOpen
• Subjects: Allium sativum; Antibiotic resistance; Antibiotics; Antiinfectives and antibacterials; Antimicrobial agents; Bacterial diseases; Bactericidal; Biogenic synthesis; Chemistry and Materials Science; Copper; Copper oxides; Doping; E coli; Escherichia coli; Garlic; Ginger; Health problems; Infections; Mastitis; Materials Science; Metal oxides; Molecular Medicine; Nano Express; Nanochemistry; Nanoparticles; Nanoscale Science and Technology; Nanotechnology; Nanotechnology and Microengineering; Public health; Synthesis; Zingiber officinale; Nanoparticles; Mastitis; Bactericidal; Doping; Garlic; Biogenic synthesis; Ginger; E. coli
• ISSN: 1931-7573; 1556-276X; 1556-276X
• DOI: 10.1186/s11671-021-03605-z

The development of resistance against antibiotics used to treat bacterial infections along with the prevalence of medication residues presents significant public health problems globally. Antibiotic-resistant germs result in infections that are difficult or impossible to treat. Decreasing antibiotic effectiveness calls for rapid development of alternative antimicrobials. In this respect, nanoparticles (NPs) of copper oxide (CuO) manifest a latent and flexible inorganic nanostructure with noteworthy antimicrobial impact. Green synthesis of CuO NPs was performed in the current study, which was then doped with varying amounts of ginger (
Zingiber officinale
, ZO) and garlic (
Allium sativum
, AS) extracts. In low and high doses, the synthesized compound was used to measure the antimicrobial effectiveness against pathogenic
Escherichia coli
. The present research successfully demonstrated a renewable, eco-friendly synthesis technique with natural materials that is equally applicable to other green metal oxide NPs.