Hematopoietic stem cell transplantation and quality of life during the first year of treatment

• Published in: Revista latino-americana de enfermagem Vol. 26; p. e3065
• Main Authors: Marques, Angela da Costa Barcellos, Szczepanik, Ana Paula, Machado, Celina Angélica Mattos, Santos, Pâmella Naiana Dias, Guimarães, Paulo Ricardo Bittencourt, Kalinke, Luciana Puchalski
• Format: Journal Article
• Language: English
• Published: Brazil Universidade de São Paulo-USP, Escola de Enfermagem de Ribeirão Preto - USP 25-10-2018; Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo; Universidade de São Paulo
• Subjects: Adolescent; Adult; Aged; Blood cancer; Bone marrow; Bone Marrow Transplantation; Bone Marrow Transplantation - psychology; Brazil; Cancer therapies; Drug Therapy; Female; Hematologic Neoplasms; Hematologic Neoplasms - psychology; Hematologic Neoplasms - surgery; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cell Transplantation - psychology; Humans; Longitudinal Studies; Male; Middle Aged; NURSING; Oncology Nursing; Original; Quality of Life; Stem cell transplantation; Surveys and Questionnaires; Young Adult; Brazil; Transplante de Medula Óssea; Calidad de Vida; Hematologic Neoplasms; Trasplante de Células Madre Hematopoyéticas; Drug Therapy; Hematopoietic Stem Cell Transplantation; Tratamento Farmacológico; Neoplasias Hematológicas; Oncology Nursing; Qualidade de Vida; Transplante de Células-Tronco Hematopoéticas; Bone Marrow Transplantation; Enfermagem Oncológica; Trasplante de Médula Ósea; Quality of Life; Tratamiento Farmacológico; Enfermería Oncológica
• ISSN: 1518-8345; 0104-1169; 1518-8345
• DOI: 10.1590/1518-8345.2474.3065

to evaluate the quality of life of adult patients with hematological cancer comparing Hematopoietic Stem Cell Transplantation modalities during the first year of treatment.
this is an observational and longitudinal research with 55 participants. Data collection was performed in six steps: before transplantation, pancytopenia, before hospital discharge, after 100, 180 and 360 days, in a reference hospital in Brazil for this treatment. The international instruments Quality of Life Questionnaire - Core 30 and Functional Assessment Cancer Therapy - Bone Marrow Transplantation were validated and translated into Portuguese (Brazil).
the mean age of participants was 36 years, 65% (n = 36) had leukemia diagnosis and 71% (n = 39) had undergone allogenic transplantation. In the Quality of Life Questionnarie - Core30 instrument, the pain symptom was significant between the first and second stages, and loss of appetite between the third and fourth stages, both in the allogenic group. In the Functional Assessment Cancer Therapy - Bone Marrow Transplantation, the functional well-being domain was significant between the third and fourth stages, also in the allogenic group.
although the aggressiveness of treatment affects quality of life, patients consider it satisfactory after the first year. There are few significant differences between autologous and allogenic patients, and both groups have recovered in the course of the process.