Importation and early local transmission of COVID-19 in Brazil, 2020

We conducted the genome sequencing and analysis of the first confirmed COVID-19 infections in Brazil. Rapid sequencing coupled with phylogenetic analyses in the context of travel history corroborate multiple independent importations from Italy and local spread during the initial stage of COVID-19 tr...

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Published in:	Revista do Instituto de Medicina Tropical de São Paulo Vol. 62; pp. e30 - 5
Main Authors:	Jesus, Jaqueline Goes de, Sacchi, Claudio, Candido, Darlan da Silva, Claro, Ingra Morales, Sales, Flávia Cristina Silva, Manuli, Erika Regina, Silva, Daniela Bernardes Borges da, Paiva, Terezinha Maria de, Pinho, Margarete Aparecida Benega, Santos, Katia Correa de Oliveira, Hill, Sarah Catherine, Aguiar, Renato Santana, Romero, Filipe, Santos, Fabiana Cristina Pereira Dos, Gonçalves, Claudia Regina, Timenetsky, Maria do Carmo, Quick, Joshua, Croda, Julio Henrique Rosa, Oliveira, Wanderson de, Rambaut, Andrew, Pybus, Oliver G., Loman, Nicholas J., Sabino, Ester Cerdeira, Faria, Nuno Rodrigues
Format:	Journal Article
Language:	English
Published:	Brazil Instituto de Medicina Tropical de Sao Paulo 01-01-2020 Instituto de Medicina Tropical Instituto de Medicina Tropical de São Paulo Universidade de São Paulo (USP)
Subjects:	Aged Betacoronavirus - genetics Brazil - epidemiology Communicable Diseases, Imported - epidemiology Communicable Diseases, Imported - transmission Communicable Diseases, Imported - virology Coronavirus Infections - epidemiology Coronavirus Infections - transmission COVID-19 Humans Middle Aged Original Pandemics Phylogeny Pneumonia, Viral - epidemiology Pneumonia, Viral - transmission public health surveillance Reverse Transcriptase Polymerase Chain Reaction SARS-CoV-2 TROPICAL MEDICINE Brazil COVID-19 Public health surveillance SARS-CoV-2
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Summary:	We conducted the genome sequencing and analysis of the first confirmed COVID-19 infections in Brazil. Rapid sequencing coupled with phylogenetic analyses in the context of travel history corroborate multiple independent importations from Italy and local spread during the initial stage of COVID-19 transmission in Brazil.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 This authors contributed equally AUTHORS’ CONTRIBUTIONS Conceptualization, Jaqueline de Jesus, Ester Sabino and Nuno Rodrigues Faria; data curation, Darlan da Silva Candido, Oliver G. Pybus and Nuno Rodrigues Faria; formal analysis, Darlan da Silva Candido, Sarah Catherine Hill, Filipe Romero, Andrew Rambaut, Nicholas James Loman and Nuno Rodrigues Faria; funding acquisition, Andrew Rambaut, Nicholas James Loman, Ester Cerdeira Sabino, Nuno Rodrigues Faria; investigation, Jaqueline de Jesus, Claudio Sacchi, Ingra Morales Claro, Flávia Cristina Silva Sales, Erika Regina Manuli, Daniela Bernardes Borges da Silva, Terezinha Maria de Paiva, Margarete Aparecida Benega, Katia Correa de Oliveira Santos, Renato Santana Aguiar, Fabiana Cristina Pereira Santos and Claudia Regina Gonçalves; methodology, Jaqueline de Jesus, Claudio Sacchi, Ingra Morales Claro, Fabiana Cristina Pereira dos Santos, Joshua Quick and Nicholas James Loman; project administration, Andrew Rambaut, Oliver G. Pybus, Nicholas James Loman, Ester Sabino and Nuno Rodrigues Faria; resources, Julio Henrique Rosa Croda and Wanderson de Oliveira, Oliver G Pybus, Andrew Rambaut, Ester Sabino and Nuno Rodrigues Faria; software, Filipe Romero, Andrew Rambaut, Nicholas J Loman; supervision, Maria do Carmo Timenetsky, Oliver G. Pybus, Ester Sabino and Nuno Rodrigues Faria; validation, Joshua Quick, Andrew Rambaut; writing – original draft, Jaqueline de Jesus, Darlan da Silva Candido and Nuno Rodrigues Faria; writing – review & editing, Andrew Rambaut, Oliver G. Pybus, Nicholas James Loman and Ester Sabino.
ISSN:	1678-9946 0036-4665 1678-9946
DOI:	10.1590/S1678-9946202062030