Accuracy of Intracranial Pressure Monitoring-Single Centre Observational Study and Literature Review

• Published in: Sensors (Basel, Switzerland) Vol. 23; no. 7; p. 3397
• Main Authors: Pelah, Adam I, Zakrzewska, Agnieszka, Calviello, Leanne A, Forcht Dagi, Teodoro, Czosnyka, Zofia, Czosnyka, Marek
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 23-03-2023; MDPI
• Subjects: Accuracy; Blood flow; Brain; Brain Injuries, Traumatic - diagnosis; brain injury; Care and treatment; Catheters; Compliance; Epidural; External pressure; Fiber Optic Technology; head trauma; Humans; Hypertension; ICP sensor; In vivo methods and tests; Injuries; Intracranial Hypertension - diagnosis; Intracranial pressure; Intracranial Pressure - physiology; intraparenchymal sensor; Ischemia; Laboratories; Literature reviews; Monitoring; Monitoring, Physiologic - methods; Observational studies; Patients; Pressure transducers; Regulatory approval; Review; Sensors; Strain gauges; Telemedicine; Transducers; Traumatic brain injury; zero drift; United Kingdom; Germany; brain injury; zero drift; intraparenchymal sensor; ICP sensor; intracranial pressure; head trauma
• ISSN: 1424-8220; 1424-8220
• DOI: 10.3390/s23073397

Intracranial hypertension and adequacy of brain blood flow are primary concerns following traumatic brain injury. Intracranial pressure (ICP) monitoring is a critical diagnostic tool in neurocritical care. However, all ICP sensors, irrespective of design, are subject to systematic and random measurement inaccuracies that can affect patient care if overlooked or disregarded. The wide choice of sensors available to surgeons raises questions about performance and suitability for treatment. This observational study offers a critical review of the clinical and experimental assessment of ICP sensor accuracy and comments on the relationship between actual clinical performance, bench testing, and manufacturer specifications. Critically, on this basis, the study offers guidelines for the selection of ICP monitoring technologies, an important clinical decision. To complement this, a literature review on important ICP monitoring considerations was included. This study utilises illustrative clinical and laboratory material from 1200 TBI patients (collected from 1992 to 2019) to present several important points regarding the accuracy of in vivo implementation of contemporary ICP transducers. In addition, a thorough literature search was performed, with sources dating from 1960 to 2021. Sources considered to be relevant matched the keywords: "intraparenchymal ICP sensors", "fiberoptic ICP sensors", "piezoelectric strain gauge sensors", "external ventricular drains", "CSF reference pressure", "ICP zero drift", and "ICP measurement accuracy". Based on single centre observations and the 76 sources reviewed in this paper, this material reports an overall anticipated measurement accuracy for intraparenchymal transducers of around ± 6.0 mm Hg with an average zero drift of <2.0 mm Hg. Precise ICP monitoring is a key tenet of neurocritical care, and accounting for zero drift is vital. Intraparenchymal piezoelectric strain gauge sensors are commonly implanted to monitor ICP. Laboratory bench testing results can differ from in vivo observations, revealing the shortcomings of current ICP sensors.