Pulsed radiofrequency : a critical review of its efficacy

• Published in: Anaesthesia and intensive care Vol. 35; no. 6; pp. 863 - 873
• Main Authors: MALIK, K, BENZON, H. T
• Format: Journal Article
• Language: English
• Published: Edgecliff Anaesthesia and Intensive Care 01-12-2007; Sage Publications Ltd. (UK); Sage Publications Ltd
• Subjects: Analgesia; Analgesia - methods; Anesthesia; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Animals; Biological and medical sciences; Care and treatment; Chronic Disease; Chronic pain; Electric Stimulation Therapy - methods; Humans; Medical sciences; Methods; Pain Management; Pain Measurement; Patient outcomes; Radio Waves - therapeutic use; Radiotherapy; Randomized Controlled Trials as Topic; Retrospective Studies; Treatment Outcome; United States; Anesthesia; pulsed radiofrequency; Chronic; chronic pain; Pain; Radiofrequency
• ISSN: 0310-057X; 1448-0271
• DOI: 10.1177/0310057x0703500603

Pulsed radiofrequency is a growingly popular pain treatment modality. However, its clinical efficacy remains controversial. In this review, the available literature on pulsed radiofrequency is critically analysed to determine its clinical efficacy. Our search of the literature for pulsed radiofrequency yielded 341 citations; after reviewing the abstracts we found 51 relevant articles. There were 4 review articles: 44 articles pertained to the application of pulsed radiofrequency by an electrode placed in the vicinity of a neural structure. Of these only two were randomised controlled trials. Of the remaining 42 articles, one was a non-randomised controlled trial, three were prospective uncontrolled trials: there were six retrospective studies, 11 case reports, eight laboratory studies, two position papers, five editorials and seven items of correspondence, while one publication reported two studies. Three articles pertained to transcutaneous application of pulsed radiofrequency. Of the two randomised controlled trials, one reported efficacy of the pulsed radiofrequency while the other reported it to be ineffective. The majority of the uncontrolled and observational studies reported clinical efficacy of pulsed radiofrequency, however many of these studies had limitations. Further randomised controlled clinical trials are recommended in order for the practising pain physician to clearly understand the role of pulsed radiofrequency in the treatment of various chronic pain syndromes.