Pulpal and periapical tissue response after direct pulp capping with endosequence root repair material and low-level laser application

• Published in: BMC oral health Vol. 22; no. 1; p. 57
• Main Authors: Alsofi, Loai, Khalil, Wafaa, Binmadi, Nada O, Al-Habib, Mey A, Alharbi, Hanan
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 04-03-2022; BioMed Central; BMC
• Subjects: Animals; Bioceramics; Calcium Hydroxide; Calcium Phosphates; Dental ceramics; Dental Pulp; Dental Pulp Capping - methods; Dental Pulp Exposure - therapy; Dentin, Secondary; Direct pulp capping; Diseases; Drug Combinations; Endosequence root repair material; Health aspects; Humans; Laser; Lasers; Lasers in medicine; Lasers in surgery; Oxides; Patient outcomes; Periapical Tissue; Predentin thickness; Rabbits; Root canal therapy; Silicates; Saudi Arabia; Bioceramics; Predentin thickness; Direct pulp capping; Endosequence root repair material; Laser
• ISSN: 1472-6831; 1472-6831
• DOI: 10.1186/s12903-022-02099-0

The study aims to investigate the pulp and periapical reaction and healing after capping with EndoSequence Root Repair Material (ERRM) combined with low-level laser application.
In 6 rabbits, pulps were exposed via class V, half of the samples received a low-level diode laser at 980 nm. Thereafter, cavities were capped with regular-set ERRM. The specimens were processed for histomorphological examination after 2 weeks and two months.
After 2 weeks, images show mild inflammation and organized odontoblasts in lased group. The non-lased group shows more severe inflammation. The predentin thickness was thicker in the lased group with statistical significance (p < 0.05). After 2 months, inflammatory cells were sparse in both lased and non-lased groups. In the periapical area, group one showed dilated blood vessels and thick fibrous connective tissues. In group two, there were more numerous maturations of PDL fibers with scattered inflammatory cells and congested blood vessel.
Using low-level laser therapy in combination with ERRM for pulp capping shortens the inflammatory phase and enhances healing.