Human Papilloma Virus infection and cervical cancer among women who sell sex in Eastern and Southern Africa: A scoping review

• Published in: Women's Health Vol. 17; p. 17455065211058349
• Main Authors: Macleod, Catriona Ida, Reynolds, John Hunter
• Format: Book Review Journal Article
• Language: English
• Published: London, England SAGE Publications 2021; Sage Publications Ltd; SAGE Publishing
• Subjects: Acetic acid; Cancer; Cancer screening; Cervical cancer; Cervix; Contraceptives; Criteria; Disease transmission; Early Detection of Cancer; Epstein-Barr virus; Epstein-Barr Virus Infections - complications; Female; Herpesvirus 4, Human; HIV; Human immunodeficiency virus; Human papillomavirus; Humans; Infections; Inspection; Medical screening; Papillomaviridae; Papillomavirus Infections - diagnosis; Papillomavirus Infections - epidemiology; Review; Reviews; Sex; Sexually transmitted diseases; STD; Uterine Cervical Neoplasms - diagnosis; Uterine Cervical Neoplasms - epidemiology; Uterine Cervical Neoplasms - prevention & control; Viruses; South Africa; Southern Africa; Eastern Africa; review; Southern Africa; Africa; Human Papilloma Virus; sex workers; cervical cancer; HPV
• ISSN: 1745-5057; 1745-5065
• DOI: 10.1177/17455065211058349

Objectives:
Women who sell sex have a high prevalence of human papilloma virus, which may cause cervical cancer. The objective of this review was to collate findings on prevalence, associated factors, screening, service provision and utilization of services in relation to human papilloma virus and cervical cancer among women who sell sex in Eastern and Southern Africa.
Methods:
A scoping review methodology was employed. Inclusion criteria were as follows: (1) empirical papers, (2) of studies conducted in Eastern and Southern Africa, (3) published in the last 10 years, and (4) addressing women who sell sex in relation to (5) human papilloma virus and cervical cancer. A thorough search of a range of databases surfaced 66 papers. Both authors applied inclusion and exclusion criteria, resulting in 14 papers being reviewed.
Results:
The reported prevalence of high-risk human papillomavirus virus varied between 23.6% and 70.5%. HIV sero-positivity, other sexually transmitted infections and Epstein-Barr virus were associated with human papilloma virus and high-grade cervical lesions. High-risk human papilloma virus was associated with women who reported younger age at first intercourse, non-barrier contraceptive use, and no history of condom use. For screening, there was overall agreement between physician- and self-collected samples. Contradictory results were found for visual inspection with acetic acid. Screening services utilization was associated with provider’s recommendation, history of sexually transmitted infections, frequency of facility visit and history of vaginal examination. A diagonal programme led to an increase in screening, attributed to the targeted services.
Conclusions:
Context is important in planning cervical cancer services. There is a need for enhanced sexually transmitted infections and viral management within cervical cancer prevention. Women who sell sex should be empowered in self-collection of stored-dry specimens, especially in resource-constrained regions. Cervical cancer screening services should be honed to the needs of women who sell sex.