Tanshinone IIA: A Promising Natural Cardioprotective Agent

Tanshinone IIA: A Promising Natural Cardioprotective Agent

Tanshinone IIA (Tan IIA) is a member of the major lipophilic components extracted from the root of Salvia miltiorrhiza Bunge, which is currently used in China and other neighboring countries to treat patients suffering from myocardial infarction (MI), angina pectoris, stroke, diabetes, sepsis, and o...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine Vol. 2012; no. 2012; pp. 1 - 7
Main Authors: Shang, Qing-hua, Huang, Li, Xu, Hao
Format: Journal Article
Language:English
Published: Cairo, Egypt Hindawi Publishing Corporation 01-01-2012
Hindawi Limited
Subjects:
Angina
Angina pectoris
Bioavailability
Cerebral infarction
Chinese medicine
Diabetes mellitus
Intestine
Kinases
Lipophilic
Myocardial infarction
Nitric oxide
Pharmacology
Potassium
Review
Rodents
Salvia miltiorrhiza
Sepsis
Sodium
China
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Summary:Tanshinone IIA (Tan IIA) is a member of the major lipophilic components extracted from the root of Salvia miltiorrhiza Bunge, which is currently used in China and other neighboring countries to treat patients suffering from myocardial infarction (MI), angina pectoris, stroke, diabetes, sepsis, and other conditions. However, Tan IIA is not easy to be absorbed through intestinal pathway. To raise the bioavailability of the herb, sodium tanshinone IIA sulfonate (STS) was developed. This paper discussed the pharmacology of Tan IIA, STS, and their potential cardioprotective effects.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Academic Editor: Keji Chen
ISSN:1741-427X
1741-4288
1741-4288
DOI:10.1155/2012/716459