Correlation Between SF-36 and Six-Minute Walk Distance in Liver Donors

• Published in: Transplantation proceedings Vol. 42; no. 9; pp. 3597 - 3599
• Main Authors: Hsieh, C.-B, Tsai, C.-S, Chen, T.-W, Chu, H.-C, Yu, J.-C, Chen, D.-R
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 01-11-2010; Elsevier
• Subjects: Biological and medical sciences; Exercise Test; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Hepatectomy - adverse effects; Hepatectomy - psychology; Humans; Liver Transplantation - adverse effects; Liver Transplantation - psychology; Longitudinal Studies; Medical sciences; Physical Fitness; Prospective Studies; Quality of Life; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surveys and Questionnaires; Taiwan; Time Factors; Tissue Donors - psychology; Tissue, organ and graft immunology; Treatment Outcome; Taiwan; Suboptimal donor; Human; Correlation; Digestive system; Evaluation scale; Liver; Psychometrics; Transplantation; Quality of life; Medicine; Treatment; Surgery; Graft; Distance
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2010.06.033

Abstract Objective We employed the 36-item short-form health survey (SF-36) and 6-minute walk distance (6MWD) to assess the quality of life (QoL) of donors after living-donor liver transplantation (LDLT). Methods This longitudinal prospective study had data collection via an interview and test or a mailed survey. Fifty-one liver LDLT donors underwent testing before and after donation using the SF-36 questionnaire and 6MWD. Results The physical component summary (PCS) of the SF-36 declined ( P < .0001) and the mental component summary (MCS) increased significantly ( P = .04) at 1 month after donation. The 6MWD declined significantly at 2 weeks after donation ( P < .0001). After standardization, there was a high correlation between PCS and 6MWD (r2 = 0.766). Conclusions Liver donation had a moderate impact on donor physical status, but enhanced mental status. Similar decreasing trends were observed in 6MWD and PCS. After donation, real physical performance predicted PCS but not MCS.