Acute Stroke Imaging Research Roadmap

• Published in: AJNR. American journal of neuroradiology Vol. 29; no. 5; pp. e23 - 1628
• Main Authors: Wintermark, Max, Albers, Gregory W
• Format: Journal Article Conference Proceeding
• Language: English
• Published: United States Am Soc Neuroradiology 01-05-2008
• Subjects: Aged; Benchmarking; Biomarkers; Brain Ischemia - diagnosis; Brain Ischemia - diagnostic imaging; Brain Ischemia - pathology; Cerebrovascular Circulation; Cluster Analysis; Databases as Topic; Diagnostic Imaging - methods; Diagnostic Imaging - standards; Diagnostic Imaging - trends; Female; Guideline Adherence; Hospital Mortality; Humans; Magnetic Resonance Angiography - methods; Magnetic Resonance Angiography - standards; Magnetic Resonance Angiography - trends; Male; Perfusion - methods; Perfusion - standards; Regression Analysis; Stroke - diagnosis; Stroke - diagnostic imaging; Stroke - pathology; Tomography, X-Ray Computed - methods; Tomography, X-Ray Computed - standards; Tomography, X-Ray Computed - trends; Validation Studies as Topic
• ISSN: 0195-6108; 0039-2499; 1936-959X; 1524-4628
• DOI: 10.1161/strokeaha.107.512319

The recent "Advanced Neuroimaging for Acute Stroke Treatment" meeting on September 7 and 8, 2007 in Washington DC, brought together stroke neurologists, neuroradiologists, emergency physicians, neuroimaging research scientists, members of the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), industry representatives, and members of the US Food and Drug Administration (FDA) to discuss the role of advanced neuroimaging in acute stroke treatment. The goals of the meeting were to assess state-of-the-art practice in terms of acute stroke imaging research and to propose specific recommendations regarding: (1) the standardization of perfusion and penumbral imaging techniques, (2) the validation of the accuracy and clinical utility of imaging markers of the ischemic penumbra, (3) the validation of imaging biomarkers relevant to clinical outcomes, and (4) the creation of a central repository to achieve these goals. The present article summarizes these recommendations and examines practical steps to achieve them.