Renal Autotransplantation and Extracorporeal Nephron-Sparing Surgery for De Novo Renal Cell Carcinoma in a Kidney Allograft

• Published in: Transplantation direct Vol. 3; no. 8; p. e122
• Main Authors: Ono, Shinichiro, Kenmochi, Takashi, Ito, Taihei, Aida, Naohiro, Otsuki, Kazunori, Akutsu, Naotake, Maruyama, Michihiro, Kusaka, Mamoru, Shiroki, Ryoichi, Hoshinaga, Kiyotaka
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 01-08-2017; Wolters Kluwer
• ISSN: 2373-8731; 2373-8731
• DOI: 10.1097/TXD.0000000000000714

De novo renal cell carcinoma (RCC) rarely occurs in kidney allografts; however, the risk of RCC in these patients is 100-fold that of the general healthy population. Although total nephrectomy has been the standard treatment for kidney allograft RCC, several authors have reported that early-stage RCC in kidney allografts was successfully treated with nephron-sparing surgery. We herein describe a new procedure involving renal autotransplantation and extracorporeal nephron-sparing surgery, which was performed to treat de novo RCC near the hilum of a transplanted kidney. In the 22 months since transplantation, the patient's renal function has been favorable, and no recurrence has been observed. In conclusion, renal autotransplantation is a feasible technique for the treatment of RCC in kidney allografts, especially RCC located near the hilum.