The effect of epidermal pigmentation on selective vascular effects of pulsed laser

The effect of epidermal pigmentation on the threshold exposure dose for inducing purpura with a tunable dye laser at 577 nm, 1.5 microseconds pulse duration, was studied in 21 human volunteers with varied genetically determined amounts of melanin. More laser energy was required to produce purpura as...

Full description

Saved in:

Bibliographic Details
Published in:	Lasers in surgery and medicine Vol. 4; no. 4; p. 365
Main Authors:	Tan, O T, Kerschmann, R, Parrish, J A
Format:	Journal Article
Language:	English
Published:	United States 1984
Subjects:	Adolescent Adult Coloring Agents Epidermis - pathology Epidermis - radiation effects Female Humans Lasers Male Maximum Allowable Concentration Purpura - etiology Purpura - pathology Radiation Dosage Rhodamines Skin - blood supply Skin Pigmentation
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The effect of epidermal pigmentation on the threshold exposure dose for inducing purpura with a tunable dye laser at 577 nm, 1.5 microseconds pulse duration, was studied in 21 human volunteers with varied genetically determined amounts of melanin. More laser energy was required to produce purpura as constitutive skin pigmentation increased. Histology showed that, in lighter skin, the laser threshold dose produced the most specific vascular injury with no disruption of surrounding structures. In more pigmented skin, damage occurred in the epidermal basal layer and very few changes were seen in blood vessels below.
ISSN:	0196-8092
DOI:	10.1002/lsm.1900040409