Cavernous Sinus Syndrome Associated with Nonsecretory Myeloma

• Published in: Internal Medicine Vol. 38; no. 12; pp. 988 - 990
• Main Authors: KYODA, Katsunori, NAKAMURA, Shinobu, TAKESHIMA, Minoru, MATANO, Sadaya, MASUDA, Shinji, MATSUDA, Tamotsu, MIYAKOSHI, Hisatsugu
• Format: Journal Article
• Language: English
• Published: Tokyo The Japanese Society of Internal Medicine 1999; Japanese Society of Internal Medicine
• Subjects: Biological and medical sciences; Humans; intracranial tumor; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Middle Aged; multiple myeloma; Multiple Myeloma - complications; Nervous system; Oculomotor Nerve Diseases - etiology; Paranasal Sinus Neoplasms - complications; plasmacytoma; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Sphenoid Sinus; Syndrome; Trigeminal Nerve Diseases - etiology; Human; Cavernous sinus; Immunopathology; Nervous system diseases; Multiple; Radiodiagnosis; Malignant hemopathy; Myeloma; Nuclear magnetic resonance imaging; Syndrome; Cerebral disorder; Case study; Pathology; Immunoglobulinopathy; Biopsy; Lymphoproliferative syndrome; Medical imagery; Complication; Plasmacytoma
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.38.988

The case of a 53-year-old man who developed cavernous sinus syndrome (CSS) four years after being diagnosed as having nonsecretory myeloma is described. He was admitted with diplopia and dull pain over the right infraorbital and zygomatic region in June 1997. The cause of CSS was the intracranial involvement of myeloma, which was diagnosed by fiberscopic biopsy. The results of endocrinologic evaluation were almost normal. The response to radiotherapy and chemotherapy was mild. CSS caused by nonsecretory myeloma is rare and its prognosis is poor. More aggressive chemotherapy with stem cell support may be indicated. (Internal Medicine 38: 988-990, 1999)