Association of lipoprotein lipase gene polymorphisms with obesity and type 2 diabetes in an Asian Indian population

Aims: Lipoprotein lipase (LPL), a pivotal enzyme in lipoprotein metabolism, catalyzes the hydrolysis of triglycerides of very low-density lipoproteins and chylomicrons. Assuming that the variants in the promoter of the LPL gene may be associated with changes in lipid metabolism leading to obesity an...

Full description

Saved in:

Bibliographic Details
Published in:	International Journal of Obesity Vol. 31; no. 6; pp. 913 - 918
Main Authors:	Radha, V, Vimaleswaran, K.S, Ashok Ayyappa, K, Mohan, V
Format:	Journal Article
Language:	English
Published:	Basingstoke Nature Publishing 01-06-2007 Nature Publishing Group
Subjects:	adults Biological and medical sciences Body Mass Index Case-Control Studies Cholesterol Control Diabetes Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Enzymes Epidemiology Etiopathogenesis. Screening. Investigations. Target tissue resistance Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Gene Frequency - genetics Genetic aspects genetic polymorphism Genetic polymorphisms genetic variation Genotype Genotype & phenotype Glucose Humans Hydrolysis India - epidemiology Insulin resistance linkage disequilibrium Linkage Disequilibrium - genetics lipid metabolism lipoprotein lipase Lipoprotein Lipase - genetics Lipoproteins Male Medical sciences Metabolic diseases Metabolism Middle Aged molecular sequence data noninsulin-dependent diabetes mellitus Obesity Obesity - epidemiology Obesity - genetics Physiological aspects Polymerase chain reaction Polymorphism, Genetic - genetics Population studies promoter regions Promoter Regions, Genetic - genetics restriction fragment length polymorphism Risk factors single nucleotide polymorphism triacylglycerols Triglycerides Type 2 diabetes Urban Health Vertebrates: anatomy and physiology, studies on body, several organs or systems very low density lipoprotein waist circumference Waist-Hip Ratio India Asia Germany Endocrinopathy Type 2 diabetes Human Obesity Asiatic Genetic variability Nutrition Enzyme Nutrition disorder Genotype Metabolic diseases LPL Esterases Lipoprotein lipase Asian Indians Carboxylic ester hydrolases Association Hydrolases Genetics Indian Population Public health Nutritional status Polymorphism
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!