Chinese medicines in the treatment of experimental diabetic nephropathy

Diabetic nephropathy (DN) is a severe micro vascular complication accompanying diabetes mellitus that affects millions of people worldwide. End-stage renal disease occurs in nearly half of all DN patients, resulting in large medical costs and lost productivity. The course of DN progression is compli...

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Bibliographic Details
Published in:	Chinese medicine Vol. 11; no. 6; p. 6
Main Authors:	Liu, Jing-Yi, Chen, Xiao-Xin, Tang, Sydney Chi-Wai, Sze, Stephen Cho-Wing, Feng, Yi-Bin, Lee, Kai-Fai, Zhang, Kalin Yan-Bo
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 24-02-2016 BioMed Central
Subjects:	Analysis Care and treatment Diabetes Diabetic nephropathies Drugs Kidney diseases Medicine, Chinese Metabolism Pathogenesis Review Rodents Studies Treatment outcome
Online Access:	Get full text
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Summary:	Diabetic nephropathy (DN) is a severe micro vascular complication accompanying diabetes mellitus that affects millions of people worldwide. End-stage renal disease occurs in nearly half of all DN patients, resulting in large medical costs and lost productivity. The course of DN progression is complicated, and effective and safe therapeutic strategies are desired. While the complex nature of DN renders medicines with a single therapeutic target less efficacious, Chinese medicine, with its holistic view targeting the whole system of the patient, has exhibited efficacy for DN management. This review aims to describe the experimental evidence for Chinese medicines in DN management, with an emphasis on the underlying mechanisms, and to discuss the combined use of herbs and drugs in DN treatment.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1749-8546 1749-8546
DOI:	10.1186/s13020-016-0075-z