Stem cell therapy: a potential for the perils of pancreatitis

• Published in: The Turkish journal of gastroenterology Vol. 31; no. 6; pp. 415 - 424
• Main Authors: Chela, Harleen, Romana, Bhupinder S, Madabattula, Markandeya, Albarrak, Abdulmajeed A, Yousef, Mohamad H, Samiullah, Sami, Tahan, Veysel
• Format: Journal Article
• Language: English
• Published: AVES 01-06-2020; Turkish Society of Gastroenterology
• Subjects: Analysis; B cells; Inflammation; Pancreatitis; Review; Stem cell research; Stem cell transplantation; Stem cells; Su Song; Transplantation
• ISSN: 2148-5607; 1300-4948; 2148-5607
• DOI: 10.5152/tjg.2020.19143

Acute and chronic pancreatitides carry a significant disease burden with no definite treatment. They are associated with local and systemic inflammation and lead to numerous complications. Stem cell therapy has been explored for treating other diseases and has gained momentum due to its implications for acute and chronic pancreatitis. Stem cell therapy not only has the potential to aid regeneration but can also prevent pancreatic injury, injury to other organs along with the resultant complications. Stem cells appear to have immunomodulatory properties and clinical potential as evidenced by numerous studies conducted on animal models. This review discusses commonly used stem cells and their respective properties that show promise for treating pancreatitis. Keywords: Stem cell, pancreas, therapy, treatment