Acute paronychia and reactive capillary proliferation in a patient on erlotinib

Sir, Erlotinib is an epidermal growth factor receptor (EGFR) inhibitor which targets epidermal growth and metastasis in solid cancers such as lung, pancreas, breast, and gastrointestinal tract. On examination, left great toe revealed an ill-defined tender, erythematous swelling in the periungual reg...

Full description

Saved in:

Bibliographic Details
Published in:	Indian journal of dermatology Vol. 65; no. 3; pp. 236 - 237
Main Authors:	Kaur, Ishmeet, Gandhi, Vijay, Jakhar, Deepak
Format:	Journal Article
Language:	English
Published:	Kolkata Wolters Kluwer India Pvt. Ltd 01-05-2020 Medknow Publications & Media Pvt. Ltd Wolters Kluwer - Medknow Wolters Kluwer Medknow Publications
Subjects:	Correspondence Debridement Granulomas Growth factors Monoclonal antibodies Staphylococcus infections Targeted cancer therapy
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Sir, Erlotinib is an epidermal growth factor receptor (EGFR) inhibitor which targets epidermal growth and metastasis in solid cancers such as lung, pancreas, breast, and gastrointestinal tract. On examination, left great toe revealed an ill-defined tender, erythematous swelling in the periungual region with a well-defined vascular growth at the junction of proximal and lateral nail folds with bloody discharge, suggestive of pyogenic granuloma. {Figure 1}{Figure 2} EGFR inhibitors including small molecule tyrosine kinase inhibitors (erlotinib and gefitinib) and their chimeric monoclonal antibody (cetuximab) are increasingly been used in the management of various solid malignancies, such as non-small cell lung cancer and pancreatic cancer.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0019-5154 1998-3611
DOI:	10.4103/ijd.IJD_348_18