Multivalent Glycocluster Design through Directed Evolution

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Bibliographic Details
Published in:	Angewandte Chemie International Edition Vol. 50; no. 47; pp. 11238 - 11242
Main Authors:	MacPherson, Iain S., Temme, J. Sebastian, Habeshian, Sevan, Felczak, Krzysztof, Pankiewicz, Krzysztof, Hedstrom, Lizbeth, Krauss, Isaac J.
Format:	Journal Article
Language:	English
Published:	Weinheim WILEY-VCH Verlag 18-11-2011 Wiley Subscription Services, Inc
Edition:	International ed. in English
Subjects:	Antibodies, Monoclonal - chemistry Azides - chemistry Base Sequence Binding Sites carbohydrates cluster effect directed evolution Directed Molecular Evolution - methods DNA - chemistry Drug Design Gene Library glycoconjugates Glycoconjugates - chemical synthesis Glycoconjugates - chemistry Glycosylation HIV Envelope Protein gp120 - chemistry Ligands Mannosides - chemistry Molecular Sequence Data multivalency Protein Binding
Online Access:	Get full text
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Bibliography:	NIH - No. R01 AI090745; No. U01 AI75466-01; No. R01 GM054403 ArticleID:ANIE201105555 ark:/67375/WNG-82MRW5J9-L I.J.K. gratefully acknowledges Brandeis University and the NIH (R01 AI090745). L.H. gratefully acknowledges the NIH (U01 AI75466-01 and R01 GM054403). istex:8FC2D3388666DB69B8121700963D2D3AD8AAA6E9 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.201105555