Transfusion-related acute Lung injury; clinical perspectives

Transfusion-related acute lung injury (TRALI) was introduced in 1983 to describe a clinical syndrome seen within 6 h of a plasma-containing blood products transfusion. TRALI is a rare transfusion complication; however, the FDA has suggested that TRALI is the leading cause of transfusion-related mort...

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Published in:Korean journal of anesthesiology Vol. 68; no. 2; pp. 101 - 105
Main Authors: Kim, Jeongmin, Na, Sungwon
Format: Journal Article
Language:English
Published: Korea (South) 대한마취통증의학회(구 대한마취과학회) 01-04-2015
The Korean Society of Anesthesiologists
Korean Society of Anesthesiologists
대한마취통증의학회
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Summary:Transfusion-related acute lung injury (TRALI) was introduced in 1983 to describe a clinical syndrome seen within 6 h of a plasma-containing blood products transfusion. TRALI is a rare transfusion complication; however, the FDA has suggested that TRALI is the leading cause of transfusion-related mortality. Understanding the pathogenesis of TRALI will facilitate adopting preventive strategies, such as deferring high plasma volume female product donors. This review outlines the clinical features, pathogenesis, treatment, and prevention of TRALI.
Bibliography:The Korean Society of Anesthesiologists
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
G704-000679.2015.68.2.006
ISSN:2005-6419
2005-7563
DOI:10.4097/kjae.2015.68.2.101