Cytomegalovirus enteritis in a premature infant

• Published in: Journal of pediatric surgery Vol. 32; no. 11; pp. 1545 - 1547
• Main Authors: Reyes, Cynthia, Pereira, Sara, Warden, M.James, Sills, Jack
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Philadelphia, PA Elsevier Inc 01-11-1997; Elsevier; Published by Elsevier Inc
• Subjects: Biological and medical sciences; Cytomegalovirus Infections - complications; Cytomegalovirus Infections - congenital; Cytomegalovirus Infections - diagnosis; Enterocolitis, Pseudomembranous - virology; Human viral diseases; Humans; Infant, Newborn; Infant, Premature; Infectious diseases; Male; Medical sciences; Viral diseases; Viral diseases of the digestive system; enteritis; Cytomegalovirus; necrotizing enteritis; colonic stricture; Human; Premature; Herpesviridae; Betaherpesvirinae; Infection; Virus; Case study; Newborn; Viral disease; Digestive diseases; Intestinal disease; Enteritis
• ISSN: 0022-3468; 1531-5037
• DOI: 10.1016/S0022-3468(97)90448-6

Background/Purpose:
Up to 2.5% of newborn infants are cytomegalovirus (CMV) positive at birth. Five percent will be symptomatic at birth, including cytomegalic inclusion disease. Symptoms such as hearing loss and mental retardation will ultimately develop in 15%.
Methods:
The authors describe a case of CMV enteritis in a 2.2-kg newborn that presented as necrotizing enterocolitis (NEC) and subsequently developed a colonic stricture.
Results:
There are four reports of neonatal CMV enteritis in the nonEnglish-language literature. Cytomegalovirus enteritis has become prevalent among the immunosuppressed pediatric and adult patient population.
Conclusions:
We propose the addition of CMV to the list of pathogens responsible for NEC. A review of neonatal CMV infection is provided.