Flavones: From Biosynthesis to Health Benefits

• Published in: Plants (Basel) Vol. 5; no. 2; p. 27
• Main Authors: Jiang, Nan, Doseff, Andrea I, Grotewold, Erich
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 21-06-2016; MDPI AG
• Subjects: biological activities; C-glycosyl transferases; cytochrome P-450; Fe2+/2-oxoglutarate-dependent dioxygenases; flavone; flavone synthase; health benefits; Review; biological activities; C-glycosyl transferases; Fe2+/2-oxoglutarate-dependent dioxygenases; cytochrome P-450; health benefits; flavone; flavone synthase
• ISSN: 2223-7747; 2223-7747
• DOI: 10.3390/plants5020027

Flavones correspond to a flavonoid subgroup that is widely distributed in the plants, and which can be synthesized by different pathways, depending on whether they contain C- or O-glycosylation and hydroxylated B-ring. Flavones are emerging as very important specialized metabolites involved in plant signaling and defense, as well as key ingredients of the human diet, with significant health benefits. Here, we appraise flavone formation in plants, emphasizing the emerging theme that biosynthesis pathway determines flavone chemistry. Additionally, we briefly review the biological activities of flavones, both from the perspective of the functions that they play in biotic and abiotic plant interactions, as well as their roles as nutraceutical components of the human and animal diet.