Epidemiology and treatment of beta thalassemia major in China

Thalassemia, classified as the main types α‐ and β‐thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is importa...

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Bibliographic Details
Published in:	Pediatric investigation Vol. 4; no. 1; pp. 43 - 47
Main Authors:	Xu, Xiaoxiao, Wu, Xuedong
Format:	Journal Article
Language:	English
Published:	Hoboken John Wiley & Sons, Inc 01-03-2020 John Wiley and Sons Inc Wiley
Subjects:	Anemia Bone marrow Chelation therapy Children & youth China Disease Epidemiology Families & family life Hospitals Iron Parents & parenting Quality of life Review Stem cells Thalassemia Transplants & implants Treatment Umbilical cord China
Online Access:	Get full text
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Summary:	Thalassemia, classified as the main types α‐ and β‐thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is important to improve patient outcomes. This paper reviews the current status of β‐thalassemia major in China, including its epidemiology and treatment.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	2574-2272 2096-3726 2574-2272
DOI:	10.1002/ped4.12154