Association Between Pandemic Coronavirus Disease 2019 Public Health Measures and Reduction in Critical Care Utilization Across ICUs in Alberta, Canada

• Published in: Critical care medicine Vol. 50; no. 3; pp. 353 - 362
• Main Authors: Bagshaw, Sean M., Zuege, Danny J., Stelfox, Henry T., Opgenorth, Dawn, Wasylak, Tracy, Fraser, Nancy, Nguyen, Thanh X.
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 01-03-2022
• Subjects: Adult; Age Factors; Aged; Alberta - epidemiology; APACHE; Bed Occupancy; Communicable Disease Control - statistics & numerical data; Comorbidity; COVID-19 - epidemiology; Critical Care; Female; Hospital Mortality; Hospitalization - statistics & numerical data; Humans; Intensive Care Units - statistics & numerical data; Male; Middle Aged; Pandemics; Patient Discharge; Public Health; Retrospective Studies; SARS-CoV-2; Sex Factors; Alberta
• ISSN: 0090-3493; 1530-0293
• DOI: 10.1097/CCM.0000000000005275

The coronavirus disease 2019 pandemic has disrupted critical care services across the world. In anticipation of surges in the need for critical care services, governments implemented "lockdown" measures to preserve and create added critical care capacity. Herein, we describe the impact of lockdown measures on the utilization of critical care services and patient outcomes compared with nonlockdown epochs in a large integrated health region.
This was a population-based retrospective cohort study.
Seventeen adult ICUs across 14 acute care hospitals in Alberta, Canada.
All adult (age ≥ 15 yr) patients admitted to any study ICU.
None.
The main exposure was ICU admission during "lockdown" occurring between March 16, 2020, and June 30, 2020. This period was compared with two nonpandemic control periods: "year prior" (March 16, 2019, to June 30, 2019) and "pre lockdown" immediately prior (November 30, 2019, to March 15, 2020). The primary outcome was the number of ICU admissions. Secondary outcomes included the following: daily measures of ICU utilization, ICU duration of stay, avoidable delay in ICU discharge, and occupancy; and patient outcomes. Mixed multilevel negative binomial regression and interrupted time series regression were used to compare rates of ICU admissions between periods. Multivariable regressions were used to compare patient outcomes between periods. During the lockdown, there were 3,649 ICU admissions (34.1 [8.0] ICU admissions/d), compared with 4,125 (38.6 [9.3]) during the prelockdown period and 3,919 (36.6 [8.7]) during the year prior. Mean bed occupancy declined significantly during the lockdown compared with the nonpandemic periods (78.7%, 95.9%, and 96.4%; p < 0.001). Avoidable ICU discharge delay also decreased significantly (42.0%, 53.2%, and 58.3%; p < 0.001). During the lockdown, patients were younger, had fewer comorbid diseases, had higher acuity, and were more likely to be medical admissions compared with the nonpandemic periods. Adjusted ICU and hospital mortality and ICU and hospital lengths of stay were significantly lower during the lockdown compared with nonpandemic periods.
The coronavirus disease 2019 lockdown resulted in substantial changes to ICU utilization, including a reduction in admissions, occupancy, patient lengths of stay, and mortality.